This Medicine Buddha practice is longer than the Medicine Buddha sadhana and includes praises and requests to each of the Medicine Buddhas as well as Shakyamuni Buddha. It is advised for individuals and centers to do on the eighth day of every Tibetan month and is also a practice to do when someone is sick, dying or has passed away.

"It is very important that the elaborate Medicine Buddha puja be done regularly in order to benefit all. Medicine Buddha puja is also something that can be done for people who are dying, or who have already passed away, and also for individual success in all kinds of activities. This Medicine Buddha practice is extremely powerful and beneficial especially when it is done with extensive offerings beautifully arranged." (Lama Zopa Rinpoche)